Dilated Cardiomyopathy Compatible With Sarcoidosis Presenting with Syncope Due to Torsades de Pointes: a Case Report


  • Carollina Fernandes Tinoco Centro Universitário de Volta Redonda – Volta Redonda/RJ – Brazil.
  • Nathalia Rodrigues Perrenoud Branca Centro Universitário de Volta Redonda – Volta Redonda/RJ – Brazil.
  • Gabriela Domingues Carvalho Centro Universitário de Volta Redonda – Volta Redonda/RJ – Brazil.
  • Lívia Silva de Paula Faria Centro Universitário de Volta Redonda – Volta Redonda/RJ – Brazil.
  • Erivelton Alessandro do Nascimento Centro Universitário de Volta Redonda – Volta Redonda/RJ – Brazil/ Universidade Federal Fluminense – Hospital Universitário Antônio Pedro – Niterói/RJ – Brazil. https://orcid.org/0000-0001-8260-6572


Sarcoidosis, Syncope, Cardiac arrhythmias, Magnetic resonance imaging


Sarcoidosis is a multisystemic noncaseating granulomatous disease of unknown etiology. Cardiac sarcoidosis clinical presentation is diverse, and syncope is one of the possible primary events. Due to its variable natural history and initial presentation associated with lacking sensitive and specific diagnostic tests, it still represents a challenging diagnosis. This article presents the case of a 51-year-old female patient with intermittent syncope events associated with torsades de pointes and dilated cardiomyopathy compatible with sarcoidosis.


Download data is not yet available.


Serei VD, Fyfe B. The Many Faces of Cardiac Sarcoidosis. American Journal of Clinical Pathology. 2020 Feb 8;153(3):294–302.

Youssef G, Beanlands RSB, Birnie DH, Nery PB. Cardiac sarcoidosis: applications of imaging in diagnosis and directing treatment. Heart. 2011 Dec 15;97(24):2078–87.

Mankad P, Mitchell B, Birnie D, Kron J. Cardiac Sarcoidosis. Curr Cardiol Rep. 2019 Dec;21(12):152.

Tan JL, Sharma S. Cardiac sarcoidosis presenting with syncope and rapidly progressive atrioventricular block. Journal of the American College of Cardiology. 2018 Mar;71(11):yty103.

Thangam M, Nathan S, Kar B, Petrovic M, Patel M, Loyalka P, et al. Primary Cardiac Sarcoidosis with Syncope and Refractory Atrial Arrhythmia: A Case Report and Review of the Literature. Texas Heart Institute Journal. 2016 Jun 1;43(3):236–40.

Lenge VV, Zurick AO, Yaddanapudi K, Flamm SD, Tan CD, Bolen MA. Cardiac and pulmonary sarcoidosis presenting as syncopal episode: Report of two cases. Radiology Case Reports. 2011;6(4):536.

Noor A, Bhatti W, Masood J. Syncope: a life threatening presentation for cardiac sarcoidosis. Chest. 2019 Oct;156(4):A388.

Verdickt S, De Man F, Haine E, Van Cleemput J. Sarcoidosis presenting as cardiac tamponade: a case report. Acta Clinica Belgica. 2020 Jan 30;1–5.

Arkema EV, Cozier YC. Epidemiology of sarcoidosis: current findings and future directions. Therapeutic Advances in Chronic Disease. 2018 Nov;9(11):227–40.

Hulten E, Aslam S, Osborne M, Abbasi S, Bittencourt MS, Blankstein R. Cardiac sarcoidosis-state of the art review. Cardiovasc Diagn Ther. 2016 Feb;6(1):50–63.

Ipek E, Demirelli S, Ermis E, Inci S. Sarcoidosis and the heart: A review of the literature. Intractable Rare Dis Res. 2015 Nov;4(4):170–80.

Kouranos V, Wells AU, Sharma R. Treatment of cardiac sarcoidosis. Current Opinion in Pulmonary Medicine. 2019 Sep;25(5):519–25.

Antunes H, Gil J, Marmelo B, Gonçalves ML, Pires MI, Santos JM, et al. Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy. IJCS [Internet]. 2020 [cited 2020 Jul 19]; Available from: http://publicacoes.cardiol.br/portal/ijcs/ingles/aop/2020/AOP_2019-0153_i.pdf

Tsushima T, Sasaki S, Yuda S, Ohta M, Cammack I, Sato H, et al. Remaining challenges in the diagnosis of early stage cardiac sarcoidosis. Clin Case Rep. 2019 May;7(5):1007–11.

Kopřiva P, Gřiva M, Tüdös Z. Management of cardiac sarcoidosis - A practical guide. Cor Vasa. 2018 Apr 1;60(2):e155–64.

Elwazir MY, Bois JP, Abou Ezzeddine OF, Chareonthaitawee P. Imaging and Quantification of Cardiac Sarcoidosis. Seminars in Nuclear Medicine. 2020 Jul;50(4):283–94.

Okada DR, Bravo PE, Vita T, Agarwal V, Osborne MT, Taqueti VR, et al. Isolated cardiac sarcoidosis: A focused review of an under-recognized entity. J Nucl Cardiol. 2018;25(4):1136–46.

Malinowska E, Doboszyńska A, Śliwińska A, Buscombe JR, Kulesza G, Moczulska B, et al. The use of 67Ga scintigraphy in patients with sarcoidosis. Nucl Med Rev Cent East Eur. 2018;21(1):59–65.

Zhang J, Li Y, Xu Q, Xu B, Wang H. Cardiac Magnetic Resonance Imaging for Diagnosis of Cardiac Sarcoidosis: A Meta-Analysis. Canadian Respiratory Journal. 2018 Dec 17;2018:1–10.

Erthal F, Juneau D, Lim SP, Dwivedi G, Nery PB, Birnie D, et al. Imaging of cardiac sarcoidosis. Q J Nucl Med Mol Imaging. 2016 Sep;60(3):252–63.

Chinitz JS, Inra LA, Stein KM, Weinsaft JW. Isolated Cardiac Sarcoid in a Patient with Unexplained Syncope. Journal of Cardiovascular Electrophysiology. 2010 Mar;21(3):333–333.

Saad Shaukat MH, Fahad F, Weinreb D, Torosoff M. Systemic sarcoidosis presenting as complete heart block in a patient with normal chest radiography. BMJ Case Rep. 2019 Mar;12(3):e227143.

Ferreira Araújo Mendes E, Carlos Pachón Mateo J, Nelson Albornoz Vargas R. Distúrbios de condução e arritmias na sarcoidose cardíaca - Relato de caso. JBAC. 2018 Dec;31(4):138–41.

Al-Khatib SM, Stevenson WG, Ackerman MJ, Bryant WJ, Callans DJ, Curtis AB, et al. 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Executive summary. Heart Rhythm. 2018 Oct;15(10):e190–252.




How to Cite

Tinoco, C. F. ., Branca, N. R. P. ., Carvalho, G. D. ., Faria, L. S. de P. ., & Nascimento, E. A. do. (2020). Dilated Cardiomyopathy Compatible With Sarcoidosis Presenting with Syncope Due to Torsades de Pointes: a Case Report. JOURNAL OF CARDIAC ARRHYTHMIAS, 34(1), 32–37. Retrieved from https://www.jca.org.br/jca/article/view/3414



Clinical Arrythmia